MSc. student
Nguyen Thi Huynh Nhu
Biotechnology Center of Ho Chi Minh City
Title: Study of vancomycin and linezolid susceptibitity among staphylococci isolated from cattle and poultry environment in southern Vietnam
Name(s): Nguyen Thi Huynh Nhu1,2, Yuri Ushijima3, Pham Thi Kim Tram1, Kazuya Morikawa3,*, Nguyen Thi Le Thuy1,*
1Biotechnology Center of Ho Chi Minh City, Vietnam
- Vietnam National University – Ho Chi Minh City University of Science
- Institute of Medicine, University of Tsukuba, Tsukuba, Japan
* Corresponding author(s): ntlthuy.shtp@tphcm.gov.vn and morikawa.kazuya.ga@u.tsukuba.ac.jp
The increasing resistance to vancomycin and linezolid in staphylococci is becoming a significant global health challenges. These antibiotics are considered last-resort agents for infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and other multidrug-resistant Gram-positive bacteria. In the context of One Health approach, antibiotic resistance in livestock environments may contribute to the transmission of resistant bacteria between animal and human. This study aimed to evaluate the susceptibility of vancomycin and linezolid in staphylococci isolated from livestock and poultry environments. A total of 122 samples were collected from 47 enterprise-affiliated and private farms between October 2023 to October 2025 in several provinces in Southern Vietnam. A total of 285 staphylococci were isolated using Mannitol salt agar plates and were confimred by Gram-staining and catalase test. Minimum inhibitory concentration (MIC) of vancomycin and linezolid of all the isolates were determined by microdilution method. Neither vancomycin-intermediate nor resistant staphylococci were detected, while one linezolid-resistant S. arlettae carrying the cfr gene was identified. Notably, the proportion of isolates with vancomycin MIC ≥ 1 µg/mL was 76,14%. Taken together, the results highlight the necessity of regular antimicrobial surveillance in livestock environment to prevent the emergence of new drug-resistant pathogens.
Biography of the presenting author
Nguyen Thi Huynh Nhu, aged 29, is currently pursuing her master’s degree at Vietnam National University – Ho Chi Minh City University of Science. Concurrently, she works as a researcher at the Medical Biotechnology Division of Biotechnology Center of Ho Chi Minh City, Vietnam. Her aspiration is to acquire comprehensive knowledge in microbiology and antimicrobal resistance field to enhance and advance her research endeavors.
Presenting author details
Full name: Nguyen Thi Huynh Nhu
Contact number: 0395659268
Email: 22c67029@student.hcmus.edu.vn
Session name/ number: Antimicrobial resistance and treatment
Category: Oral presentation